Small molecule delivery through nanofibrous scaffolds for musculoskeletal regenerative engineering
نویسندگان
چکیده
منابع مشابه
Aligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering
Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...
متن کاملNanofibrous Scaffolds for Tissue Engineering Applications
The discipline of tissue engineering opens up the ways for repair and regenerate damaged organs and tissues. In the current work biomimetic nanofibrous scaffolds were fabricated by electrospinning. Poly-L-lactic acid (PLLA) was blended with collagen and gelatin to fabricate PLLLA-collagen and PLLA-gelatin fibrous scaffolds respectively. Pure PLLA and gelatin scaffolds served as controls. All th...
متن کاملMeniscus Tissue Engineering with Nanofibrous Scaffolds
The fibrocartilaginous menisci dwell between the articular surfaces of the knee and play a central role in joint function. Damage through trauma or degenerative changes is a common orthopaedic injury, disrupts the meniscus mechanical function, and leads to the precocious development of osteoarthritis. The current standard of treatment is removal of the damaged tissue, a procedure that does not ...
متن کاملaligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering
aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (pcl), poly (vinyl alcohol) (pva) and hydroxyapatite nanoparticles (nha). the morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...
متن کاملAligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering
Objective(s): Biological effects of MSCs on aligned and random nanofibrous scaffolds of PCL/PVA/nHA were investigated in this study. Materials and Methods: Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were eval...
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ژورنال
عنوان ژورنال: Nanomedicine: Nanotechnology, Biology and Medicine
سال: 2014
ISSN: 1549-9634
DOI: 10.1016/j.nano.2014.05.013